The production team behind the live-action drama Anmetto: A Neurosurgeon’s Diary (アンメット ある脳外科医の日記) has officially confirmed that 10 regular cast members from the first season will return for the upcoming sequel, led by Ryuya Wakaba.

About the Series

Based on the manga by Yuzuru Koshika and Kanto Otsuki, which ran in Kodansha’s Morning magazine from 2020 to 2024 across 17 collected volumes, the series follows Miyabi Kawauchi, a neurosurgeon who suffers brain damage in an accident and develops a memory disorder, yet continues to pour everything into saving her patients while rebuilding her own life. The first TV drama season aired in April 2024 with Hana Sugisaki in the lead role. Season 2 picks up approximately two and a half months after the finale of Season 1, depicting “the life that follows” as Miyabi returns to work as a neurosurgeon. The new season will blend story elements from the original manga with original content.

Returning Cast

• Ryuya Wakaba — Tomoharu Sanpei, Miyabi’s fiancé and fellow neurosurgeon
• Amane Okayama (岡山天音) — Kaede Ayano
• Kazumi Yamaya (山谷花純) — Hinako Mori
• Takumi Ozaki (尾崎匠海) of INI — Hiori Kazama
• Riho Nakamura (中村里帆) — Koharu Arai
• Junpei Yasui (安井順平) — Toshiyuki Todo
• Kayo Noro (野呂佳代) — Takako Narimasu
• Michiko Yoshise (吉瀬美智子) — Reiko Tsubata
• Mariko Akama (赤間麻里子) — Yoshimi Kashiwagi, manager of Bistro Lagoon, the team’s favourite gathering spot
• Arata Iura (井浦新) — Koichi Osako, Miyabi’s attending physician

Cast Comments

Ryuya Wakaba (Tomoharu Sanpei): “When I was first approached about Season 2, my honest reaction was, ‘What more is there to tell?’ I was sceptical enough that I even thought about who else could play Sanpei if I didn’t come back. But after reading the project proposal, I was strongly convinced — there were things left undone, things that still needed to be told. The very next day I said, ‘I’m in.’ I’ll have you glued to your screens.”

Amane Okayama (Kaede Ayano): “I feel deeply honoured to once again be part of the world of Anmetto as Kaede Ayano. I want to find out for myself, through Ayano, what lies at the end of holding on to a feeling that’s always on the verge of slipping away.”

Kazumi Yamaya (Hinako Mori): “I’m savouring the joy of returning to the world of Anmetto as Hinako Mori. One for all, all for one — I believe that spirit, which fills the set, will reach the audience on the other side of the screen.”

Takumi Ozaki (Hiori Kazama): “The more I face Kazama, the more I feel his gentleness, his awkwardness, and his sincere desire to be there for others. In this season I hope to grow alongside him.”

Riho Nakamura (Koharu Arai): “Getting to return to a set full of memories I want to revisit again and again, to reunite with everyone at Kyuryo Central Hospital — my heart hasn’t stopped racing at the thought of those days coming back.”

Junpei Yasui (Toshiyuki Todo): “Two years have passed since I said I wanted to create a miracle with this production. I feel joy down to my very cells at being able to live once more as Director Todo in the world of Anmetto.”

Kayo Noro (Takako Narimasu): “Anmetto is back after two years. I’m so happy to see the cast and crew again, and I’m looking forward to creating something wonderful together with the new additions as well.”

Michiko Yoshise (Reiko Tsubata): “I hear this season will weave together the original manga and new original content — I’m personally excited to see how the story unfolds. Tsubata overcame her trauma in Season 1; I hope to show a slightly softer, more grown version of her this time.”

Mariko Akama (Yoshimi Kashiwagi): “I’m grateful for the chance to give something back to the doctors who looked after my character. I’ll do my very best to provide a warm, healing space for everyone.”

Arata Iura (Koichi Osako): “There is a quiet joy and a tension in being able to live as Osako again. He always stands one step back, rarely speaking his true feelings — yet beneath that surface lie conflicts and unspoken wishes he has carried for a long time. I want to carefully unravel that inner movement as I portray him in this new chapter.”

Premiere Date

Anmetto: A Neurosurgeon’s Diary Season 2 is set to premiere on January 4, 2027. New cast members who will bring fresh turbulence to the story will be announced at a later date.